Pick, R., He, W., Chen, C., Scheiermann, C. Time-Of-Day Dependend Trafficking and Function of Leukocyte Subsets. Trends in Immunology 2019 In press.

Ince, L., Weber, J., Scheiermann, C. Control of Leukocyte Trafficking by Stress-Associated Hormones. Frontiers in Immunology 2019 9:3143.


He, W., Holtkamp, S., Hergenhan, S., Kraus, K., de Juan, A., Weber, J., Bradfield, P., Grenier, J., Pelletier, J., Druzd, D., Chen, C., Ince, L., Bierschenk, S., Pick, R., Sperandio, M., Scheiermann, C. Circadian Expression of Migratory Factors
Establishes Lineage-Specific Signatures that Guide the Homing of Leukocyte Subsets to Tissues. Immunity. 2018 49: 1–16.

Moretti FA., Klapproth S., Ruppert R., Margraf A., Weber J., Pick R., Scheiermann C., Sperandio M., Fässler R., Moser M. Differential requirement of kindlin-3 for T-cell progenitor homing to the non-vascularized and vascularized thymus. eLIFE. 2018 7:e35816.

Scheiermann, C., Gibbs, J., Ince, L., & Loudon, A. Clocking in to immunity. Nature Reviews Immunology. 2018 18:423–437. Cover

Winter, C., Silvestre-Roig, C., Ortega-Gomez, A., Lemnitzer, P., Poelman, H., Schumski, A., Winter, J., Drechsler, M., de Jong, R., Immler, R., Sperandio, M., Hristob, M., Zeller, T., Nicolaes, G., Weber, C., Viola, J., Hidalgo, A., Scheiermann, C., Soehnlein, O., Chrono-pharmacologial Targeting of the CCL2-CCR2 Axis Ameliorates Atherosclerosis. Cell Metabolism. 2018 28:175–182.

Stremmel, C., Schuchert, R., Wagner, F., Thaler, R., Weinberger, T., Pick, R., Mass, E., Ishikawa-Ankerhold, H., Margraf, A., Hutter, S., Vagnozzi, R., klapproth, S., Frampton, J., Yona, S., Scheiermann, C., Molkentin, D., Jeshke, U., Moser, M., Sperandio, M., Massberg, S., Geissmann, F., Schulz, C. Yolk sac macrophage progenitors traffic to the embryo during defined stages of development. Nature Communications. 2018 9(75).


Druzd, D., Matveeva, O., Ince, L., Harrison, U., He, W., Schmal, C., Herzel, H., Tsang, A., Kawakami, N., Leliavski, A., Uhl, U., Yao, L., Sander, L., Chen, C., Kraus, K., de Juan, A., Hergenhan, S., Ehlers, M., Koletzko, B., Haas, R., Solbach, W., Oster, H. and Scheiermann, C. Lymphocyte circadian clocks control lymph node trafficking and adaptive immune responses. Immunity. 2017 46:120-132. Cover & Best of Immunity 2017 (


Campa, C.C., Germena, G., Ciraolo, E., Copperi, F., Sapienza, A., Franco, I., Ghigo, A., Camporeale, A., Di Savino, A., Martini, M., Perino, A., Megens, R.T., Kurz, A.R., Scheiermann, C., Sperandio, M., Gamba, A., and Hirsch, E. Rac signal adaptation controls neutrophil mobilization from the bone marrow. Sci Signal. 2016 9:ra124.

Ortega-Gomez, A., Salvermoser, M., Rossaint, J., Pick, R., Brauner, J., Lemnitzer, P., Tilgner, J., de Jong, R.J., Megens, R.T., Jamasbi, J., Döring, Y., Pham, C.T., Scheiermann, C., Siess, W., Drechsler, M., Weber, C., Grommes, J., Zarbock, A., Walzog, B., and Soehnlein, O.. Cathepsin G Controls Arterial But Not Venular Myeloid Cell Recruitment. Circulation. 2016 134:1176-1188.

Schloss, M.J., Horckmans, M., Nitz, K., Duchene, J., Drechsler, M., Bidzhekov, K., Scheiermann, C., Weber, C., Soehnlein, O., and Steffens, S. The time-of-day of myocardial infarction onset affects healing through oscillations in cardiac neutrophil recruitment. EMBO Mol Med. 2016 8:937-48.


Alard, J.E., Ortega-Gomez, A., Wichapong, K., Bongiovanni, D., Horckmans, M., Megens, R.T., Leoni, G., Ferraro, B., Rossaint, J., Paulin, N., Ng, J., Ippel, H., Suylen, D., Hinkel, R., Blanchet, X., Gaillard, F., D’Amico, M., von Hundelshausen, P., Zarbock, A., Scheiermann, C., Hackeng, T.M., Steffens, S., Kupatt, C., Nicolaes, G.A., Weber, C. und Soehnlein, O. Recruitment of classical monocytes can be inhibited by disturbing heteromers of neutrophil HNP1 and platelet CCL5. Sci. Trans. Med. 2015 7:317ra196.

Zhang, D., Chen, G., Manwani, D., Mortha, A., Xu, C., Faith, J. J., Burk, R. D., Kunisaki, Y., Jang, J. E., Scheiermann, C., Merad, M., and Frenette, P. S. Neutrophil ageing is regulated by the microbiome. Nature. 2015 525:528-32.

Scheiermann, C., Frenette, P. S. and Hidalgo, A. Regulation of leukocyte homeostasis in the circulation. Cardiovasc. Res. 2015 107:340-51.


Bruns, I., Lucas, D., Pinho, S., Ahmed, J., Lambert, M. P., Kunisaki, K., Scheiermann, C., Schiff, L., Poncz, M., Bergman, A., and Frenette, P. S. Megakaryocytes regulate haematopoietic stem cell quiescence via Cxcl4 secretion. Nat. Med. 2014 20:1315-20.

Druzd, D., de Juan, A., and Scheiermann, C. Circadian rhythms in leukocyte trafficking. Semin. Immunopathol. 2014 36:149-62.


Kunisaki, Y., Bruns, I., Scheiermann, C., Ahmed, J., Pinho, S., Zhang, D., Mizoguchi, T., Wei, Q., Lucas, D., Ito, K., Mar, J. C., Bergman, A., and Frenette, P. S. Arteriolar niches maintain haematopoietic stem cell quiescence. Nature. 2013 502:637-43

Druzd, D. and Scheiermann, C. Some monocytes got rhythm. Science. 2013 341:1462-4.

Lucas, D., Scheiermann, C., Chow, A., Kunisaki, Y., Bruns, I., Barrick, C., Tessarollo, L., and Frenette, P. S. Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration. Nat. Med. 2013 19:695-703

Scheiermann, C., Kunisaki Y., and Frenette, P. S. Circadian control of the immune system. Nat. Rev. Immunol. 2013 13:190-8.

Frenette, P. S., Pinho, S., Lucas, D., and Scheiermann, C. Mesenchymal Stem Cell: Keystone of the Hematopoietic Stem Cell Niche and a Stepping-Stone for Regenerative Medicine. Annu. Rev. Immunol. 2013 31:285-316.


Scheiermann, C., Kunisaki, Y., Lucas, D., Chow, A., Jang, J. E., Zhang, D., Hashimoto, D., Merad, M., and Frenette, P. S. Adrenergic nerves govern circadian leukocyte recruitment to tissues. Immunity. 2012 37:290-301.

Almeida, C. B., Scheiermann, C., Jang, J. E., Prophete, C., Costa, F. F., Conran, N., and Frenette, P. S. Hydroxyurea and a cGMP-amplifying agent have immediate benefits on acute vaso-occlusive events in sickle cell disease mice. Blood. 2012 120:2879-88.


Chow, A., Lucas, D., Hidalgo, A., Méndez-Ferrer, S., Hashimoto, D., Scheiermann, C., Battista, M., Leboeuf, M., Prophete, C., van Rooijen, N., Tanako, M., Merad, M., and Frenette, P. S. Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche. J. Exp. Med. 2011 208:261-71.


Scheiermann, C., Kunisaki, Y., Jang, J., and Frenette, P. S. Neutrophil microdomains: linking heterocellular interactions with vascular injury. Curr. Opin. Hematol. 2010 17:25-30.

2005 – 2009

Scheiermann, C., Colom, B., Meda, P., Patel, N. S., Voisin, M. B., Marrelli, A., Woodfin, A., Pitzalis, C., Thiemermann, C., Aurrand-Lions, M., Imhof, B. A., and Nourshargh, S. Junctional adhesion molecule-C mediates leukocyte infiltration in response to ischemia reperfusion injury. Arterioscler. Thromb. Vasc. Biol. 2009 29:1509-15.

Scheiermann, C., Meda, P., Aurrand-Lions, M., Madani, R., Yiangou, Y., Coffey, P., Salt, T. E, Ducrest-Gay, D., Caille, D., Howell, O., Reynolds, R., Lobrinus, A., Yu, A. S., Adams, R. H., Anand, P., Imhof, B. A., and Nourshargh, S. Expression and function of junctional adhesion molecule-C in myelinated peripheral nerves. Science 2007 318:1472-1475.

Bradfield, P. F., Scheiermann, C., Nourshargh, S., Ody, C., Luscinskas, F. W., Rainger, G. E., Nash, G. B., Miljkovic-Licina, M., Aurrand-Lions, M., and Imhof, B. A. JAM-C regulates unidirectional monocyte transendothelial migration in inflammation. Blood 2007 110:2545-2555.

Woodfin, A., Reichel, C. A., Khandoga, A., Corada, M., Voisin, M. B., Scheiermann, C., Haskard, D. O., Dejana, E., Krombach, F., and Nourshargh, S. JAM-A mediates neutrophil transmigration in a stimulus-specific manner in vivo: evidence for sequential roles for JAM-A and PECAM-1 in neutrophil transmigration. Blood 2007 110:1848-56.

Howell, O. W., Palser, A., Polito, A., Melrose, S., Zonta, B., Scheiermann, C., Vora, A. J., Brophy, P. J., and Reynolds, R. Disruption of neurofascin localization reveals early changes preceding demyelination and remyelination in multiple sclerosis. Brain 2006 129:3173-85.

Wang, S., Voisin, M. B., Larbi, K. Y., Dangerfield, J., Scheiermann, C., Tran, M., Maxwell, P. H., Sorokin, L., and Nourshargh, S. Venular basement membranes contain specific matrix protein low expression regions that act as exit points for emigrating neutrophils. J. Exp. Med. 2006 203:1519-32.

Huang, M. T., Larbi, K. Y., Scheiermann, C., Woodfin, A., Gerwin, N., Haskard, D. O., and Nourshargh, S. ICAM-2 mediates neutrophil transmigration in vivo: evidence for stimulus specificity and a role in PECAM-1-independent transmigration. Blood 2006 107:4721-4727.

Nencioni, A., Hua, F., Dillon, C. P., Yokoo, R., Scheiermann, C., Cardone, M. H., Barbieri, E., Rocco, I., Garuti, A., Wesselborg, S., Belka, C., Brossart, P., Patrone, F., and Ballestrero, A. Evidence for a protective role of Mcl-1 in proteasome inhibitor-induced apoptosis. Blood 2005 105:3255-62.