Publications

2017

Druzd, D., Matveeva, O., Ince, L., Harrison, U., He, W., Schmal, C., Herzel, H., Tsang, A., Kawakami, N., Leliavski, A., Uhl, U., Yao, L., Sander, L., Chen, C., Kraus, K., de Juan, A., Hergenhan, S., Ehlers, M., Koletzko, B., Haas, R., Solbach, W., Oster, H. and Scheiermann, C. Lymphocyte circadian clocks control lymph node trafficking and adaptive immune responses. Immunity. 2017 46:120-132. Cover

2016

Campa, C.C., Germena, G., Ciraolo, E., Copperi, F., Sapienza, A., Franco, I., Ghigo, A., Camporeale, A., Di Savino, A., Martini, M., Perino, A., Megens, R.T., Kurz, A.R., Scheiermann, C., Sperandio, M., Gamba, A., and Hirsch, E. Rac signal adaptation controls neutrophil mobilization from the bone marrow. Sci Signal. 2016 9:ra124.

Ortega-Gomez, A., Salvermoser, M., Rossaint, J., Pick, R., Brauner, J., Lemnitzer, P., Tilgner, J., de Jong, R.J., Megens, R.T., Jamasbi, J., Döring, Y., Pham, C.T., Scheiermann, C., Siess, W., Drechsler, M., Weber, C., Grommes, J., Zarbock, A., Walzog, B., and Soehnlein, O.. Cathepsin G Controls Arterial But Not Venular Myeloid Cell Recruitment. Circulation. 2016 134:1176-1188.

Schloss, M.J., Horckmans, M., Nitz, K., Duchene, J., Drechsler, M., Bidzhekov, K., Scheiermann, C., Weber, C., Soehnlein, O., and Steffens, S. The time-of-day of myocardial infarction onset affects healing through oscillations in cardiac neutrophil recruitment. EMBO Mol Med. 2016 8:937-48.

2015

Alard, J.E., Ortega-Gomez, A., Wichapong, K., Bongiovanni, D., Horckmans, M., Megens, R.T., Leoni, G., Ferraro, B., Rossaint, J., Paulin, N., Ng, J., Ippel, H., Suylen, D., Hinkel, R., Blanchet, X., Gaillard, F., D’Amico, M., von Hundelshausen, P., Zarbock, A., Scheiermann, C., Hackeng, T.M., Steffens, S., Kupatt, C., Nicolaes, G.A., Weber, C. und Soehnlein, O. Recruitment of classical monocytes can be inhibited by disturbing heteromers of neutrophil HNP1 and platelet CCL5. Sci. Trans. Med. 2015 7:317ra196.

Zhang, D., Chen, G., Manwani, D., Mortha, A., Xu, C., Faith, J. J., Burk, R. D., Kunisaki, Y., Jang, J. E., Scheiermann, C., Merad, M., and Frenette, P. S. Neutrophil ageing is regulated by the microbiome. Nature. 2015 525:528-32.

Scheiermann, C., Frenette, P. S. and Hidalgo, A. Regulation of leukocyte homeostasis in the circulation. Cardiovasc. Res. 2015 107:340-51.

2014

Bruns, I., Lucas, D., Pinho, S., Ahmed, J., Lambert, M. P., Kunisaki, K., Scheiermann, C., Schiff, L., Poncz, M., Bergman, A., and Frenette, P. S. Megakaryocytes regulate haematopoietic stem cell quiescence via Cxcl4 secretion. Nat. Med. 2014 20:1315-20.

Druzd, D., de Juan, A., and Scheiermann, C. Circadian rhythms in leukocyte trafficking. Semin. Immunopathol. 2014 36:149-62.

2013

Kunisaki, Y., Bruns, I., Scheiermann, C., Ahmed, J., Pinho, S., Zhang, D., Mizoguchi, T., Wei, Q., Lucas, D., Ito, K., Mar, J. C., Bergman, A., and Frenette, P. S. Arteriolar niches maintain haematopoietic stem cell quiescence. Nature. 2013 502:637-43

Druzd, D. and Scheiermann, C. Some monocytes got rhythm. Science. 2013 341:1462-4.

Lucas, D., Scheiermann, C., Chow, A., Kunisaki, Y., Bruns, I., Barrick, C., Tessarollo, L., and Frenette, P. S. Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration. Nat. Med. 2013 19:695-703

Scheiermann, C., Kunisaki Y., and Frenette, P. S. Circadian control of the immune system. Nat. Rev. Immunol. 2013 13:190-8.

Frenette, P. S., Pinho, S., Lucas, D., and Scheiermann, C. Mesenchymal Stem Cell: Keystone of the Hematopoietic Stem Cell Niche and a Stepping-Stone for Regenerative Medicine. Annu. Rev. Immunol. 2013 31:285-316.

2012

Scheiermann, C., Kunisaki, Y., Lucas, D., Chow, A., Jang, J. E., Zhang, D., Hashimoto, D., Merad, M., and Frenette, P. S. Adrenergic nerves govern circadian leukocyte recruitment to tissues. Immunity. 2012 37:290-301.

Almeida, C. B., Scheiermann, C., Jang, J. E., Prophete, C., Costa, F. F., Conran, N., and Frenette, P. S. Hydroxyurea and a cGMP-amplifying agent have immediate benefits on acute vaso-occlusive events in sickle cell disease mice. Blood. 2012 120:2879-88.

2011

Chow, A., Lucas, D., Hidalgo, A., Méndez-Ferrer, S., Hashimoto, D., Scheiermann, C., Battista, M., Leboeuf, M., Prophete, C., van Rooijen, N., Tanako, M., Merad, M., and Frenette, P. S. Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche. J. Exp. Med. 2011 208:261-71.

2010

Scheiermann, C., Kunisaki, Y., Jang, J., and Frenette, P. S. Neutrophil microdomains: linking heterocellular interactions with vascular injury. Curr. Opin. Hematol. 2010 17:25-30.

2005 – 2009

Scheiermann, C., Colom, B., Meda, P., Patel, N. S., Voisin, M. B., Marrelli, A., Woodfin, A., Pitzalis, C., Thiemermann, C., Aurrand-Lions, M., Imhof, B. A., and Nourshargh, S. Junctional adhesion molecule-C mediates leukocyte infiltration in response to ischemia reperfusion injury. Arterioscler. Thromb. Vasc. Biol. 2009 29:1509-15.

Scheiermann, C., Meda, P., Aurrand-Lions, M., Madani, R., Yiangou, Y., Coffey, P., Salt, T. E, Ducrest-Gay, D., Caille, D., Howell, O., Reynolds, R., Lobrinus, A., Yu, A. S., Adams, R. H., Anand, P., Imhof, B. A., and Nourshargh, S. Expression and function of junctional adhesion molecule-C in myelinated peripheral nerves. Science 2007 318:1472-1475.

Bradfield, P. F., Scheiermann, C., Nourshargh, S., Ody, C., Luscinskas, F. W., Rainger, G. E., Nash, G. B., Miljkovic-Licina, M., Aurrand-Lions, M., and Imhof, B. A. JAM-C regulates unidirectional monocyte transendothelial migration in inflammation. Blood 2007 110:2545-2555.

Woodfin, A., Reichel, C. A., Khandoga, A., Corada, M., Voisin, M. B., Scheiermann, C., Haskard, D. O., Dejana, E., Krombach, F., and Nourshargh, S. JAM-A mediates neutrophil transmigration in a stimulus-specific manner in vivo: evidence for sequential roles for JAM-A and PECAM-1 in neutrophil transmigration. Blood 2007 110:1848-56.

Howell, O. W., Palser, A., Polito, A., Melrose, S., Zonta, B., Scheiermann, C., Vora, A. J., Brophy, P. J., and Reynolds, R. Disruption of neurofascin localization reveals early changes preceding demyelination and remyelination in multiple sclerosis. Brain 2006 129:3173-85.

Wang, S., Voisin, M. B., Larbi, K. Y., Dangerfield, J., Scheiermann, C., Tran, M., Maxwell, P. H., Sorokin, L., and Nourshargh, S. Venular basement membranes contain specific matrix protein low expression regions that act as exit points for emigrating neutrophils. J. Exp. Med. 2006 203:1519-32.

Huang, M. T., Larbi, K. Y., Scheiermann, C., Woodfin, A., Gerwin, N., Haskard, D. O., and Nourshargh, S. ICAM-2 mediates neutrophil transmigration in vivo: evidence for stimulus specificity and a role in PECAM-1-independent transmigration. Blood 2006 107:4721-4727.

Nencioni, A., Hua, F., Dillon, C. P., Yokoo, R., Scheiermann, C., Cardone, M. H., Barbieri, E., Rocco, I., Garuti, A., Wesselborg, S., Belka, C., Brossart, P., Patrone, F., and Ballestrero, A. Evidence for a protective role of Mcl-1 in proteasome inhibitor-induced apoptosis. Blood 2005 105:3255-62.